Lu Gan Selected Research

mavorixafor

1/2022	Mavorixafor, an Orally Bioavailable CXCR4 Antagonist, Increases Immune Cell Infiltration and Inflammatory Status of Tumor Microenvironment in Patients with Melanoma.
1/2021	A phase 1b trial of the CXCR4 inhibitor mavorixafor and nivolumab in advanced renal cell carcinoma patients with no prior response to nivolumab monotherapy.

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Lu Gan Research Topics

Disease

114	Neoplasms (Cancer) 05/2024 - 06/2003
28	Inflammation (Inflammations) 04/2024 - 03/2010
16	Breast Neoplasms (Breast Cancer) 01/2023 - 01/2014
15	Neoplasm Metastasis (Metastasis) 11/2023 - 09/2011
14	Stomach Neoplasms (Stomach Cancer) 11/2023 - 08/2012
10	Obesity 02/2024 - 09/2014
10	Hepatocellular Carcinoma (Hepatoma) 01/2023 - 10/2005
9	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 01/2022 - 01/2015
8	Infections 02/2024 - 10/2009
8	Insulin Resistance 01/2023 - 12/2013
8	Graves Ophthalmopathy 01/2023 - 05/2016
7	Mitochondrial Diseases (Mitochondrial Disease) 02/2024 - 04/2013
7	Ischemia 06/2023 - 09/2010
7	Reperfusion Injury 01/2022 - 09/2010
7	Lung Neoplasms (Lung Cancer) 01/2021 - 05/2011
7	Carcinogenesis 01/2020 - 02/2009
6	Fibrosis (Cirrhosis) 01/2024 - 05/2011
6	Cognitive Dysfunction 01/2024 - 01/2015
6	Prostatic Neoplasms (Prostate Cancer) 12/2023 - 12/2008
6	Necrosis 01/2023 - 11/2017
6	Body Weight (Weight, Body) 08/2018 - 01/2012
5	Psoriasis (Pustulosis Palmaris et Plantaris) 04/2024 - 01/2017
5	Cardiovascular Diseases (Cardiovascular Disease) 03/2024 - 10/2007
5	Colorectal Neoplasms (Colorectal Cancer) 06/2023 - 01/2021
5	Wounds and Injuries (Trauma) 04/2023 - 06/2010
5	Stroke (Strokes) 01/2022 - 01/2015
5	Myocardial Ischemia (Ischemic Heart Diseases) 01/2022 - 01/2019
4	Hypertension (High Blood Pressure) 01/2024 - 01/2019
4	Uterine Cervical Neoplasms (Cancer of the Cervix) 01/2023 - 01/2015
4	Rheumatoid Arthritis 09/2022 - 08/2014
4	Hepatitis 01/2022 - 07/2012
4	Urinary Bladder Neoplasms (Bladder Cancer) 01/2022 - 03/2014
4	Parkinson Disease (Parkinson's Disease) 01/2022 - 01/2019
4	Heart Failure 01/2022 - 12/2014
4	Myocardial Infarction 01/2022 - 01/2016
4	Infarction (Infarctions) 11/2020 - 09/2010
4	Dermatitis 03/2019 - 01/2017
4	Huntington Disease (Huntington's Disease) 02/2007 - 11/2002
3	Melanoma (Melanoma, Malignant) 01/2023 - 01/2022
3	Diabetes Mellitus 03/2022 - 07/2009
3	Esophageal Squamous Cell Carcinoma 01/2022 - 10/2013

Drug/Important Bio-Agent (IBA)

33	Proteins (Proteins, Gene)FDA Link 11/2022 - 11/2002
17	Biomarkers (Surrogate Marker)IBA 01/2023 - 01/2015
13	CytokinesIBA 04/2023 - 06/2003
13	CarbonIBA 01/2023 - 01/2014
13	Messenger RNA (mRNA)IBA 01/2020 - 04/2004
12	Doxorubicin (Adriamycin)FDA LinkGeneric 11/2023 - 08/2014
11	MicroRNAs (MicroRNA)IBA 04/2024 - 09/2015
9	RNA (Ribonucleic Acid)IBA 01/2024 - 09/2016
8	Reactive Oxygen Species (Oxygen Radicals)IBA 02/2024 - 08/2010
8	Immune Checkpoint InhibitorsIBA 11/2023 - 01/2021
8	Glucose (Dextrose)FDA LinkGeneric 01/2023 - 01/2012
7	LipidsIBA 01/2023 - 12/2012
7	AntioxidantsIBA 01/2020 - 09/2010
6	LipopolysaccharidesIBA 04/2023 - 01/2017
6	Insulin (Novolin)FDA Link 03/2022 - 05/2014
5	Imiquimod (Aldara)FDA LinkGeneric 04/2024 - 01/2017
5	Eosine Yellowish-(YS) (Eosin)IBA 04/2024 - 09/2011
5	Hematoxylin (Haematoxylon)IBA 04/2024 - 09/2011
5	AntibodiesIBA 10/2023 - 12/2012
5	Fatty Acids (Saturated Fatty Acids)IBA 01/2023 - 04/2014
5	Peptides (Polypeptides)IBA 01/2023 - 10/2009
5	Therapeutic UsesIBA 01/2023 - 02/2006
5	Transcription Factors (Transcription Factor)IBA 01/2023 - 02/2009
5	Troleandomycin (TAO)FDA Link 02/2022 - 05/2016
5	ThioredoxinsIBA 01/2021 - 10/2005
5	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 03/2019 - 01/2014
5	Small Interfering RNA (siRNA)IBA 01/2019 - 08/2012
4	LigandsIBA 10/2023 - 01/2019
4	InflammasomesIBA 06/2023 - 08/2017
4	Interleukin-6 (Interleukin 6)IBA 08/2022 - 04/2018
4	Hydrogen Peroxide (Hydroperoxide)FDA LinkGeneric 01/2022 - 10/2009
4	DNA (Deoxyribonucleic Acid)IBA 01/2022 - 12/2017
4	Docetaxel (Taxotere)FDA Link 01/2021 - 11/2009
4	Glutathione (Reduced Glutathione)IBA 01/2021 - 09/2010
4	FlavonoidsIBA 01/2020 - 06/2016
4	Drug CarriersIBA 01/2019 - 05/2015
4	ChemokinesIBA 07/2018 - 01/2016
3	Antiviral Agents (Antivirals)IBA 02/2024 - 10/2009
3	CateninsIBA 01/2024 - 01/2023
3	Neoplasm Antigens (Tumor Antigens)IBA 11/2023 - 12/2022
3	B7-H1 AntigenIBA 11/2023 - 07/2020
3	Sirtuin 1IBA 06/2023 - 01/2016
3	alpha-Tocopherol FDA Link 01/2023 - 01/2022
3	beta Carotene (Betacarotene)FDA Link 01/2023 - 01/2022
3	AntigensIBA 01/2023 - 06/2020
3	Hormones (Hormone)IBA 03/2022 - 12/2013
3	Cisplatin (Platino)FDA LinkGeneric 01/2022 - 12/2017
3	DiterpenesIBA 01/2022 - 01/2021

Therapy/Procedure

67	Therapeutics 03/2024 - 10/2007
25	Drug Therapy (Chemotherapy) 10/2023 - 11/2009
16	Radiotherapy 01/2023 - 12/2010
9	Immunotherapy 11/2023 - 01/2019
5	Neoadjuvant Therapy 11/2023 - 11/2015
4	Castration 12/2023 - 11/2009
4	Lasers (Laser) 01/2023 - 01/2018
4	Chinese Traditional Medicine (Traditional Chinese Medicine) 01/2022 - 09/2016
3	Decompression 01/2023 - 04/2020
3	Moxibustion 09/2022 - 06/2019
3	Precision Medicine 01/2022 - 02/2020